International Journal of Pharmacy and Pharmacology

Abstract: Based on multilayer dielectric model, for the spherical biological cell subjected to pulsed electric field (PEF), a simplified equivalent circuit was presented. According to a mathematical analysis of a monocycle electric pulse (MEP), the relationship between a given pulse duration and a center frequency was established and its main energy was concentrated on the center frequency. Thus the transmenbrane potential of external and inner membranes induced by the MEP with various durations was simply calculated by usin…

Abstract: The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the above strategy in particular to pharmacy regulations. Under the pressure of the new privatisation policy, the government introduced radical changes in the pharmacy regulations. The 2001 Pharmacy and Poisons Act and its provisions established the Federal Pharmacy and Poison Board (FPPB)…

Abstract: The aim of this study was to investigate the effects of 12 week aerobic exercise program on health related fitness components and blood lipids in obese girls. In this study, a total of 40 girls were recruited as exercise group (n = 20) and control group (n = 19). Participants joined sessions for 60 min per day, 3 days per week for 12-week. There were significant differences in weight, body mass index (BMI), flexibility, sit-ups, hand grip for both hands, VO2max, skin fold measurements (thigh, triceps, biceps, abdom…

Abstract: The purpose of the present study is to determine the effect of eight weeks zinc supplementation on the erythrocyte and leukocyte counts and other hematological parameters in male kick boxers. Twenty-four subjects were included in the study. They were equally divided into three groups as follows: Group EZ, training and receiving 2.5 mg/kg zinc supplement per day; Group SZ, receiving the zinc supplement but no training and Group E, who exercised but received no supplement. Erythrocyte, platelet and leukocyte counts…

Abstract: Probiotics are living organisms which upon ingestion in certain numbers exert health benefits beyond inherent basic nutrition. The lactic acid bacteria are one of the most significant groups of probiotic organisms. These bacteria are commonly used in fermented dairy products and have been advocated for the treatment of gastrointestinal disorders. The aim of the present study is to investigate the effect of a probiotic strain Lactobacillus plantarum isolated from Iranian traditional cheese on gastric ulcer. Gastric…

Abstract: The aim of this study was to examine the mechanism of green tea in treating a broad spectrum of human diseases and to develop a safe and effective agent for antimicrobial and anti-inflammatory application. Catechin-enriched green tea extract (CEGTE) was prepared containing 83.15 ± 0.79% of total catechins. In vitro antimicrobial and in vivo anti-inflammatory effects were investigated and safety was evaluated in vivo with relevant positive controls. CEGTE was found to have significant bacteriostatic effects in all t…

Abstract: Preliminary phytochemical screening of the ethanol leaves of Cissampelos mucronata revealed the presence of reducing sugars, cardiac glycosides, resin, tannins, saponins, glycosides, flavonoids, glycerin and steroids. The median lethal dose (LD50) in rats is greater than 5000 mg/kg body weight intaperitoneally. The hypoglycemic effect of ethanol extract of C. mucronata was also investigated in Streptozocin - induced diabetic rats. Single intraperitoneally administration of the extract at the doses of 200, 400 and 8…

Abstract: The aim of the present study was to evaluate in vivo the anti-inflammatory, antinociceptive and ulcerogenic properties of indomethacin tablets based on solidified reverse micellar solution (SRMS). SRMS consisting of mixtures of phospholipid (Phospholipon® 90H) and triglyceride (Softisan® 154) were prepared in the ratios of 1:1, 2:1 and 1:2, respectively. SRMS based tablets containing 75 mg of indomethacin each were prepared using validated plastic mould. The physicochemical properties of the tablet formulations wer…

Abstract: The current research was conducted with the objective of developing a practical laboratory of Veterinary Pharmacology course, specifically for the purpose of evolving a practical part of the theory in the chapter of general anesthetics. The practice of the evaluation of drugs acting on the central nervous system in this discipline has difficulty with the choice of experimental model, because sometimes there are no laboratory animals such as rats, mice or rabbits; however, it is possible to use larger animals such a…

Abstract: The antifungal activity of Mentha piperita L. essential oil and its comparison with synthetic menthol on Aspergillus niger growth have been determined in vitro. The chemical compositions of essential oil of M. piperita provided from the aerial parts of plants grown in a village in Kerman Province in June 2012 were determined. The sample was cleaned and then dried in the shade. Essential oil was made by hydro-distillation method and analyzed by capillary gas chromatography (GC) using flame ionization (FID) and capil…

Abstract: Correct knowledge of current antimalarial drugs available for malaria treatment by Nigerians has a significant impact on the overall success of the ongoing national malaria control programme. This is as a result of a large segment of the communities, who more often than not, rely on self medications or as care givers influence the choice drugs for malaria treatment for their wards. The study was therefore set up to ascertain the types of drugs used for self medication of malaria among adult women in Makurdi city. T…

Abstract: The objective of the study was to identify prevalence, types and predictors of potential drug-drug interactions (pDDIs) in pulmonology ward and to report common interactions. Medical records of 400 randomly-selected patients were reviewed for pDDIs using Micromedex Drug-Reax software. Logistic-regression was applied to determine predictors of pDDIs. We identified 126 interacting-combinations that encountered in total 558 pDDIs with median number of 01 pDDI per patient. Overall 45% patients had at least one pDDI; 24…