International Journal of Pharmacy and Pharmacology

Abstract: This study aimed at synthesizing population-based studies on prevalence of hypertension in Nigeria from 1990 to 2009. General databases and subject-specific databases were searched for primary studies. Manuscripts of appropriate studies were retrieved. Based on some criteria, only eligible studies were included in the study. A total of 9 studies all from South-West region of Nigeria that fulfilled the inclusion criteria were retrieved. Prevalence of hypertension ranged from a minimum of 12.4% to a maximum of 34.8%…

Abstract: Sex is a natural and basic drive of human beings. In Malaysia, erectile dysfunction (ED) is a common problem, affecting 16 to 47% of men above 40 years old. Erectile dysfunction (ED) is a common complication of diabetics, with prevalence ranging between 27 and 75%. Knowledge and perception are essential precursors of ED related quality of life. A cross-sectional study was conducted in Pulau Pinang, Malaysia, to produce the preliminary information to compare the knowledge and the perception of diabetic and non diabe…

Abstract: Drug therapy is the most commonly used method of any disease treatment in general practice. However, the patterns of drug prescription are often inappropriate and the need for registration of these patterns is essential in an effort to improve prescription standards. Retrospective analysis of prescriptions written by various cadres in primary health care department with emphasis on primary health care centers, dispensaries and health posts in four randomly selected local government areas were collected over a perio…

Abstract: International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 8 (2), pp. 001-003, February, 2019. © International Scholars Journals Editorial Quality use of antidepressants: how Pharmacists can play their part

Abstract: This study investigated the phytoconstituents in Neem (seed and flower), Jatropha curcas (stem and root bark) and grape (stem bark and leaves) in some selected solvents. Phytochemical screening revealed the presence of bioactive compound saponin in all the parts of the three plants in water extract only. Saponin was absent in other solvents used (ethanol, ethyl acetate, propan-2-ol, methanol, n-butanol and acetone). Ethanol, ethyl acetate and methanol were the most promising solvents to extract flavonoids in both t…

Abstract: The ethanol extract of the dried leaves of Mikania cordata (Family-Asteraceae) was investigated for its possible bioactive chemical groups and antinociceptive, cytotoxic and antibacterial activities in animal models. The extract produced significant writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 125 and 250 mg/kg body weight (p[...]

Abstract: In existing study, we carried out an efficient record of the comparative antioxidant activity in methanolic extract of the selected parts (leaves, root and stem bark) of Aegle marmelos. Total content of phenol and flavonoid was quantitatively estimated in different parts of A. marmelos. The total phenolic contents varied from 9.8367 ± 0.0235 to 1.7281 ± 0.049 mg g-1. Total flavonoid contents were between 8.248 ± 0.029 to 1.087 ± 0.002 mg g-1. Free radical scavenging activity of different extracts was evaluated by u…

Abstract: The radical scavenging activity using 1,1-diphenyl, 2-picrylhydrazyl (DPPH) and cytotoxicity using sulphorhodamine B (SRB) assay of the aqueous methanolic extract of Tamarix nilotica (Ehrenb.) Bunge (Tamaricaceae) flowers and its subextracts (CHCl3, EtOAC and Pet.ether) were evaluated. Total phenolic and flavonoid contents were estimated using colorimetric assays. Ethyl acetate (EtOAc) showed the highest free radical scavenging activity with inhibitory concentration (IC50) 7.25 ± 0.86 µg/ml in addition to potential…

Abstract: Ruta graveolens is known as Rue. R. graveolens extracts and essential oil are important areas in drug development with numerous pharmacological activities in many countries. For a long time R. graveolens has been used in traditional medicines for the relief of pain, eye problems, rheumatism and dermatitis. R. graveolens has recently been shown to have antibacterial, analgesic, anti-inflammatory, antidiabetic and insecticidal activities. Rutin, quercetin, psoralen, methoxypsoralen, rutacridone, rutacridone epoxide a…

Abstract: Ficus religiosa is being used in Ayurvedic and Malay traditional medicine for the treatment of various diseases including gastric ulcer. Considering the above claims, the present work was undertaken to validate the anti-ulcer potential of the ethanol extract of stem bark of F. religiosa against in vivo indomethacin- and cold restrained stress-induced gastric ulcer, and pylorus ligation assays. The extract (100, 200 and 400 mg/kg) significantly (P[...]

Abstract: Garcinia kola is widely consumed habitually and used as traditional remedy for various diseases in Nigeria. However, information with respect to the effect of using different solvents of extraction on its antioxidant properties is scanty. Therefore, the present study investigates the effect of different solvents on the phytochemical constituents and antioxidant properties of G. kola. Phytochemicals measured were the total phenolics, flavonoids and vitamin C content while the antioxidant parameters assessed were the…

Abstract: Quantification of bioactive principles through modern analytical tools is essential for establishing the authenticity and creditability of prescription and usage of herbal drugs. In the present study, simultaneous quantification of vasicine and vasicinone, present in SIDA species (Malvaceae), by reverse phase HPLC and HPTLC methods were developed. In the RP-HPLC method, the extracts were resolved using a mobile phase of acetonitrile - 0.1 M phosphate buffer - glacial acetic acid (15:85:1, V/V/V) with pH 4.0 on a C1…

Abstract: The ethno medicinal plant Basella alba belongs to the family Basellaceae, and commonly known as malabar spinach, indian spinach, ceylon spinach and vine spinach. Although it has been reported in ancient systems of medicine, it did not gain much importance and has always remained controversial. It has been found to be a good source of calcium, iron, vitamin A and vitamin C. In the Indian system of medicine, the plant has immense potential in androgenic activity, antiulcer activity, antioxidant, cytotoxic and antibac…

Abstract: The ethanol extract of the dried leaves of Mikania cordata (Family-Asteraceae) was investigated for its possible bioactive chemical groups and antinociceptive, cytotoxic and antibacterial activities in animal models. The extract produced significant writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 125 and 250 mg/kg body weight (p[...]