International Journal of Public Health and Epidemiology

Abstract: The present study was undertaken to evaluate the possible ameliorating effect of crocin and curcumin on certain biochemical alterations associated with iron overload-induced liver injury in rats. 5 groups of rats were used, a normal control group received daily i.p. injections of saline and 4 groups received daily i.p. injections of ferric nitrilotriacetate (FeNTA) for 8 successive days, the dose of iron was increased during the experimental period (from 6 to 15 mg Fe/kg). The first iron overloaded group kept witho…

Abstract: In the present study, the hepatoprotective activity of methanolic extract of Apium graveolens L. (celery) seeds was tested against Di-(2- ethylhexyl) phthalate (DEHP) induced hepatotoxicity in rats. Oral administration of DEHP (1000 mg/kg b.wt/day) for 6 weeks in rats caused a significant increase in the levels of serum marker enzymes like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatases (ALP) and the levels of total bilirubin and hepatic lipid pe…

Abstract: Herbal drug therapy is a common practice adopted in traditional and alternative medicine and has been used in the treatment of neonatal jaundice or hyperbilirubinemia from ancient times. This is done with the help of different herbal extracts and using different treatment methods. The knowledge of new possibilities and the fact that herbal drugs have been used in some communities for a long time, clarifies the importance of studying herbal drugs. Herbal drug therapies are used commonly which amplifies the need to e…

Abstract: The aqueous extract of Cassia sieberiana stem bark was administered to groups of 4 albino rats (160 ± 10 g) at 0, 20, 60 or 180 mg/kg body weight daily by gavages for six weeks. A 7% decrease in mean body weight gain was observed in the group treated with the highest concentration of the extract (180 mg/kg). Groups treated with the extract showed significant (p < 0.05) increase in serum ALT and AST activity. Significant (p < 0.05) increase in serum urea and creatinine concentrations, together with decrease in serum…

Abstract: Industrialization has excessively modified the discharge and distribution of arsenic in the environment through natural and anthropogenic activities. Gastrointestinal tract, Lung and Dermal absorptions account for various adverse effects associated with arsenic toxicity. The knowledge of arsenic biotransformation holds the trivalent species (DMA3+ and MMA3+) accountable for most arsenic toxicity with mechanisms of action such as the inhibition of DNA replicating or repair enzymes, interference with tissue respirati…

Abstract: An investigation was conducted on the pH, nutritional and cost benefit of the use of different substrates for the production of Curvularia pallescens Boedijn. The growth of the organism was examined at pH range between 5.5 and 8.6 and on different growth media, potato carrot agar (PCA), potato dextrose agar (PDA), sabouraud agar (SA), tap water agar (TWA), water hyacinth agar (WHA) and Czapek-Dox agar (ZA). Also, the growth of the organism was examined on different enrichment media “Czapek-Dox” with its sodium nitr…

Abstract: A major feature of infection with trypanosomes is the development of anaemia. In this study, the effect of Scoparia dulcis ( Atiotiousha in Akoko-Edo) on Trypanosoma brucei induced anaemia was investigated in fifteen rabbits divided into three groups of n = 5 over a period of twenty eight days. Changes in Packed cell volume (PCV), Haemoglobin (Hb) concentration, Red blood cell count (RBC), Mean cell haemoglobin (MCH), Mean cell haemoglobin concentration, (MCHC) and Mean cell volume (MCV) were monitored over the per…

Abstract: Accepted 05 March, 2021 Introduction: The prevalence of the hepatitis B infection is estimated at 9.1% in Burkina Faso. We aimed at describing the epidemiological and clinical features of the disease. Materials and methods: we implemented a cross-sectional study from January 1st, 2004 to December 31st, 2015. Patients aged more than 15 years with positive HBsAg for over six months and positive HbeAg were included. Results: We analyzed the data of 148 participants. The sex ratio was three; 69% of the participants wer…

Abstract: Hepatocellular carcinoma (HCC) became a prevalent disease in many populations worldwide. It initiates many economic problems in management modalities and leads to increasing mortality rates. Many trials are made all over the world to implement specific early markers for detection and prediction of the disease, hoping to set a more precise strategy for liver cancer prevention. Unfortunately, many economic, cultural and disciplinary levels contribute to confounding preventive strategies. Many risk factors seem to pre…

Abstract: COVID-19 is a new pandemic disease that is affecting almost every country with a negative impact on social life and economic activities. The number of infected and deceased patients continues to increase globally. Mathematical models can help in developing better strategies to contain a pandemic. Considering multiple measures taken by African governments and challenging socio-economic factors, simple models cannot fit the data. We studied the dynamical evolution of COVID-19 in selected African countries. We estimat…