International Journal of Pharmacy and Pharmacology

Abstract: 19F NMR provided a highly specific tool for identification of efavirenz in human serum and pharmaceutical preparations as well as a suitable analytical technique for their absolute quantification. The method is based on the integration of appropriate signals of efavirenz and potassium fluoride, as an internal standard. The proposed method is simple and reliable, but when it is used without any sample pretreatment, there is a manipulation of large sample volumes and lengthy analysis time. The calibration curve for e…

Abstract: High dose statin medication in acute coronary syndrome cases is a therapy which lowers mortality and morbidity rates. Interleukin-6 (IL-6) is produced in higher amounts in acute myocardial infarction (MI) and facilitates myocardial damage. However, secretion of nitric oxide (NO) is depleted. We aimed to compare the effects of conventional dose (10-40 mg/day) and aggressive dose (80 mg/day) atorvastatin medications on IL- 6 and NO levels in patients with primary percutaneous transluminal coronary angioplasty (PTCA)…

Abstract: The ability to convert potent herbal medicines into robust tablet will require a good understanding of certain critical factors such as effect of binder concentration on granule particles and tablets properties. In this study, granules of AM-1, a prototype herbal extract has been produced by the wet granulation process of massing and screening using different concentrations of maize starch gel as binder. The effect of the binder concentrations and granule particles’ size on the granules’ flow and moisture uptake ch…

Abstract: A new, simple, specific, accurate and precise reversed phase-high performance liquid chromatography (RP-HPLC) method was developed for the determination of levofloxacin in rat plasma and saliva was developed. An HPLC system based on a Phenomenex Luna C18 Column (250 × 4.6 mm) and a UV detector ( = 296 nm) were used. A mixture of Acetonitrile: water (80:20 v/v) adjusted to pH 3.5 by orthophosphoric acid at a flow rate of 1.4 ml/min was used as mobile phase. The proteins were precipitated with methanol. The average r…

Abstract: In order to evaluate the effects of methamphetamine on sexual behavior of fish, saltwater-acclimatized male sailfin molly Poecilia latipinna L. (Pisces) adults were exposed to 0.1, 0.5, 1 mg/L methamphetamine (MA) concentrations and were observed for alterations in sexual behavior at 2nd, 5th or 7th exposure days. The overall changes displayed by the subjected fish included different acute and chronic responses.[...]

Abstract: Worldwide drug expenditures have been one of the main concerns of health care managers, and its containment is one of the primary goals of health care authorities. The present study was conducted through a cross sectional survey in Pakistan during January to June, 2010 not only to find out the importance and influence of promotional tools used by pharmaceutical industry on prescribing behaviors of doctors/consultants, but to also establish comparison between doctors/consultants versus medical representatives and co…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-005, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Evaluating the Antiplasmodial Activity of Sphenocentrum jollyanum Pierre Leaf and Root Extracts In Vivo O. S. Olorunnisola* and A. J. Afolayan School of Biological Sciences, University of Fort Hare, Alice 5700, South Africa. Accepted 16 January, 2025 Methanolic leaf and root extracts of Sphenoce…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-008, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper The Effects of Baicalin on Lipopolysaccharide-Induced Uterine Endometrium Damage and Implantation Failure in a Murine Model Yantao Zhao1, Yongzhan Bao1, Wanyu Shi1,2, Xiaodan Wang2 and Xiuhui Zhong1,2* 1College of Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China. 2Ins…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-010, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Review Exploring the Phytochemical Profile and Therapeutic Potential of Kaempferia galanga L. Muhammad Ihtisham Umar1*, Mohammad Zaini Bin Asmawi1, Amirin Sadikun2, Rabia Altaf1 and Muhammad Adnan Iqbal3 1Department of Pharmacology, School of Pharmaceutical Sciences, University Sains Malaysia, 11800 Pulau Pinang Malaysia…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-007, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Bioavailability Study of Four Aspirin Brands Marketed in Nigeria: An In Vitro-In Vivo Correlation Analysis Bamigbola E. A.1*, Ibrahim M. A.2, Attama A. A.3 and Uzondu A. L.1 1Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmacy, Madonna University, Elele, Rivers State…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-008, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Transdermal Delivery of Ligustrazine Phosphate Using Microemulsions: A Formulation Investigation Ying Cui1,2, Lingzhi Li1,2, Jun Gu1, Ting Zhang3* and Li Zhang1 1Department of Medicine Chemistry, Logistics University of Chinese People’s Armed Police Forces, Tianjin 300162, P. R. China. 2Tianjin…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-005, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper The Influence of Chloroquine on Chlorpropamide Pharmacokinetics in Healthy Volunteers Danlami U.1*, Odunola M. T.2, Magaji G.2 and Thomas S. A.1 1Sheda Science and Technology Complex (SHESTCO), P.M.B. 186, Garki, Abuja, Nigeria. 2Department of Pharmaceutical and Medicinal Chemistry, Faculty of P…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (3), pp. 001-008, March, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Regulation of Connexin Expression by Angiotensin Modulators (Losartan and Ramipril) in Vascular Injury Xujuan Li, Deqiang Li, Jinfeng Duan, Junzhu Chen, Wei Cai* and Voonthow Kok The First Affiliated Hospital, College of Medicine, Zhejiang University, No.79, Qingchun Road, Hangzhou, Zhejiang Pro…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (4), pp. 001-010, April, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Inotropic Activity Assessment of a Newly Synthesized Estradiol Derivative Using Isolated Rat Heart Preparations Figueroa-Valverde L.1*, Díaz-Cedillo F.2, López-Ramos M.1, García-Cervera E1 and Pool-Gómez E.1 1Laboratory of Pharmaco-Chemistry, Faculty of Chemical Biological Sciences, Universidad…

Abstract: International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 14 (4), pp. 001-005, April, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals Full Length Research Paper Diabetic Wound Healing: Stimulatory Effects of Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Rats Jafari Naveh H. R.1, Taghavi M. M.1*, Shariati M.1,2, Vazeirnejad R.3 and Rezvani M. E.4 1Department of Anatomy, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. 2…