Advanced Journal of Microbiology Research

Abstract: Evidence for a potential link between periodontal disease and coronary heart disease (CHD) has accumulated in recent years. C-reactive protein is potential marker of cardiovascular risk and associated with periodontal disease. CRP levels were analyzed in 26 periodontitis patients and 23 healthy controls along with hemoglobin, red blood cell count (RBC), leukocyte cell count (total and differential WBC), platelet count. Total WBC, neutrophil and platelet counts and CRP levels were raised significantly in periodontit…

Abstract: The study focused on the determination of the levels of lead, cadmium, sodium and potassium in the blood of selected industrial workers (n = 36), residents of the neighboring communities (n = 36) as well as the residents of the communities further away from any industrial setting (which controls) (n = 12). The subjects were recruited from the granite served as the, ceramic and cement industries at Ewekoro, Abeokuta North and South Local government areas of Ogun state, Nigeria. The blood lead (BPb) and cadmium (BCd)…

Abstract: The objective of this work is assessment of the toxicological effects of the organophosphorus compounds (methidathion and chlorpyrifos) and the usefulness of some parameters as bioindicators. Haematology and serum biochemistry were assayed in 15 cockrels at random age of 4 - 6 weeks. The birds were randomly assigned to 3 oral (by mouth) pulse-dose treatments of 0, 3.5 mg/kg chlorpyrifos, and 7.5 mg/kg methidathion, respectively. Haematology and serum biochemistry were used as indices of toxicosis. Significantly (P…

Abstract: Previous studies reported on relationship between chloroquine administration, insulin and glucose homeostasis, but the role of dietary fat and the combined effect of the drugs on liver function have not been exploited. The present study was set up to investigate the effect of combined administration of insulin and chloroquine on serum transferase and phosphates activity during increased dietary fat and calcium consumption. Thirty (30) adult male albino rats randomly assigned into five (5) groups were used in the st…

Abstract: The therapeutic potential of the crude extract of Dissotis rotundifolia was investigated in rats infected with Trypanosoma b. brucei. Animals were treated orally or intraperitoneally at 200, 600 and 800 mg/kg body weight. At 800 mg/kg, parasitemia was reduced by 66.7 and 78.4% after oral and intraperitoneal administration respectively. In vitro exposure of blood forms to high concentration (800 mg/kg) crude extract test resulted in complete paralysis or killing within 45 s of exposure. It is concluded that D. rotun…

Abstract: Lipase in oilseeds helps to hydrolyze the ester bonds of storage triacylglycerols. The crude lipase from the conophor nut (Tetracarpidium conophorum) was isolated and assayed via quantification of the free fatty acids liberated by the hydrolysis of the oilseed triacylglycerols. Optimum pH and temperature for the enzyme activity of the conophor nut lipase was pH 8.0 and at 30°C with substantial lipolysis at 80°C, underscoring the thermostability of the enzyme. The effects of different ions on the activity of the iso…

Abstract: Cell-free extracts of nitrate- grown mycelia of Aspergillus terreus could catalyze the hydrolytic deami-nation of cytidine to uridine and ammonia followed by the hydrolytic cleavage of the N-glycosidic bond of the produced uridine to the corresponding base (uracil) and ribose. The same extracts could not catalyze the hydrolytic deamination of cytosine. Addition of inorganic arsenate to the reaction mixture containing cytidine or uridine did not affect the amount of ribose liberated indicating the absence of pyrimid…

Abstract: Advanced Journal of Microbiology Research Vol. 2017 Available online at http://internationalscholarsjournals.org/journal/ajmr © 2017 International Scholars Journals Full Length Research Paper Lipid profile of a population of diabetic patients attending Nigerian National Petroleum Corporation Clinic, Abuja Ugwu, C. E1*. , Ezeanyika, L. U. S.2, Daikwo, M. A.1 and Amana, R.1 1Department of Biochemistry, Kogi State University, Anyigba, Nigeria. 2Department of Biochemistry, University of Nigeria, Nsukka, Nigeria. Accept…