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Gali Abaka Umaru*, Junaidu Kabir, Veronica J. Umoh, Mohammed Bello, and Jacob K. P. Kwaga
Abstract: A study was conducted to determine the occurrence of vancomycin resistant S. aureus (VRSA) in milk in Nigeria. Fourty seven S. aureus were isolated from the 372 milk samples examined, out of which 20 (5.4%) were vancomycin-resistant. Fifteen (4%) of the VRSA were isolated from raw milk, 4 (1.1%) from bulk milk and 1 (0.3%) from pasteurized milk. No significant difference (P > 0.05) between the occurrence among the study variables was observed, . No VRSA occurred in the yogurt and ‘kindirmo’ samples examined. The decrease in the occurrence of the pathogen from  raw milk to pasteurized milk and its absence in yogurt and ‘kidirmo’ suggest that pasteurization and fermentation may have eliminated most of the organisms. The resistance profiles of the VRSA isolates to other antibiotics showed high resistance to penicillin (100%), tetracycline (85%), amoxicillin (65%), methicillin (40%) and oxacillin (40%), but low to amikacin (5%) and sulphamethoxazole/trimethoprim (10%). None of the isolates were resistant to chloramphenicol and ciprofloxacin. The multiple antibiotic resistance index result revealed that 80% of the VRSA were resistant to 3 or more antibiotics. The presence of VRSA coupled with the multple resistance patterns of these isolates are of great concern and also of public health significance. Therefore more studies on the epidemiology of this pathogen in foods are required.[...] Read More.
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Ernest E. Fon, Abiya E. Acha, and Wilfred A. Abia,
Abstract: Alcohol has a strong effect on people and can cause major health problems, including liver cirrhosis and injuries in consumer’s bodies. In Cameroon, data on alcohol consumption levels as well as its influences on youth psychology and education are currently non-existing. The aim of this survey was to determine beer consumption patterns amongst students in higher institutions of learning in Buea, Cameroon, in relations to students’ lifestyles, health history and academic performances. Structured questionnaires were randomly administered to some 280 students. A total of 200 responses (males: 56.5%; females: 43.5%) were obtained from students who consume beer. Beer consumption practices were directly associated with students monthly pocket allowances. Averagely, students who drank beer consumed 1.7 L/day. This may partly justify the observed alcohol intoxication related symptoms including nausea, memory loss, accidents as revealed by survey findings. Generally, beer intake correlated negatively with student’s attitude toward their studies and positively with violence as well as nasty practices such as unconscious sexual behaviours; pointing at risk of HIV infections.  This preliminary survey has for the first time in Cameroon provided data on beer intake and its effects on student’s health, behaviours and attitude towards their education.[...] Read More.
Keywords: Alcohol, students’, academic performances, behavioural practices, health situations.
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Hassan AO, Oladeji AO, Osinowo K,  Ajuwon AJ,  Atibioke OP, Ojomo OA, Ehimatie B and Ladipo OA
Abstract: Young persons are disproportionately affected by the impact of HIV in Nigeria. This paper presents findings from an evaluation of a national youth HIV prevention program designed to determine the effects of HIV prevention intervention (HPI) on Youths on Compulsory National Service (YoCNS) and Adolescents in Secondary Schools (AiSS). Data were collected from 229 YoCNS who received training on HIV prevention and 231 of their counterparts who did not. Among AiSS, data were collected from 909 respondents who were trained as peer educators and among 1005 students who were not. Data were collected in six states namely Akwa-Ibom, Enugu, Gombe, Kaduna, Plateau and Osun using a questionnaire that explored knowledge on HIV and sexual behavior and supplemented by focus group discussions and in-depth interviews. Results show that both youths and students who received HPI reported superior knowledge on HIV/AIDS than their counterparts who did not. Students in the intervention sites also reported fewer numbers of multiple sexual partners (9.7%) compared to those in the comparison sites (15.4%). The qualitative data shows that the project had positive effects on both youths and students who received the intervention. Given these positive outcomes, it is recommended that the project should not only be sustained but expanded to reach adolescents who are out of school.[...] Read More.
Keywords: HIV prevention intervention, Youths on National Service, Adolescents in Secondary Schools, Peer education, Knowledge on HIV.
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Mabvuto Kango
Abstract: Zambia’s Petauke district experienced a plague epidemic in 2007, where there were a total of 425 cases and two deaths. What could have contributed to such a large number of cases? Due to the changing rainfall (and other climatic conditions) patterns, outbreaks of diseases such as plague are likely to recur. Identification and sharing of some of the lessons learned can greatly contribute to reducing morbidity and preventing mortality in future. The article presents a Case study of the 2007 Plague Epidemic in Zambia that highlights what went right and what went wrong in responding to the epidemic.[...] Read More.
Keywords: Zambia, lessons learned, plague, rainfall patterns, outbreak.
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Irappa Madabhavi, Swaroop Revannasiddaiah and Priyanka Das
Abstract: Tuberculosis is known from ancient times. Recently HIV and Tuberculosis emerged as an important treatable co-epidemic especially in developing countries. Extra-Pulmonary Tubercular involvement is one of the important manifestations of Tuberculosis especially in HIV co-infected patients. But the extra-pulmonary manifestations vary between patients of Tuberculosis with HIV and without HIV co infection. In HIV subgroup lymph node tuberculosis (58.1%) was commonest extra pulmonary presentation with cervical lymph nodes (35.5%) as commonest site. Neurological tuberculosis (32.3%) was second common followed by pleural effusion (29%).  Abdominal tuberculosis (19%) was at fourth place with hepatomegaly and omental mass as commonest clinical finding. Ascites was not seen in any of the patient. None of patients with HIV co infection had skeletal and pericardial involvement. EPTB most commonly affects the younger economically productive section of the society. Co-infection with HIV is an important risk factor. The site of organ involvement in EPTB is different in HIV-infected and non-HIV-infected persons. There is higher frequency of disseminated disease among HIV – TB co-infected patients.[...] Read More.
Keywords: Tuberculosis, HIV, extra pulmonary TB (EPTB) manifestations, co- infection, epidemics.
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Bernard Ortwer Atu, Ifeoma Nancy I. Obijiaku* and Sabo Ezemuel Yakubu
Abstract: Pathogenic intestinal protozoa have been associated with human gastrointestinal disorders worldwide. This study was designed to determine the prevalence & associated risk factors of Cryptosporidium parvum (CP), Entamoeba histolytica (EH) and Giardia lamblia (GL) infections in people living in the senatorial districts of Benue state (zones A, B and C). A cross-sectional study was designed in which 733 stool samples were collected from out-patients and apparently healthy individuals from homes. Ethical consent was sought and approved before sample collection. Samples were analyzed using the Rida® Quick immunochromatographic method. A structured questionnaire was administered to subjects to obtain information on their socio-demographic characteristics. The results showed a total prevalence rate of 47.8, 31.5 and 43.9% in zones A, B and C respectively. While source of drinking water was positively associated with protozoa infections in zones A and C, age, hand washing habit and source of food were statistically significant only in zone A (p < 0.05). In zone B, literacy level, household toilet facility and care of fruits significantly increased infection rates (p < 0.05). This study has identified specific risk factors responsible for pathogenic protozoa infections in humans in Benue state.[...] Read More.
Keywords: Cryptosporidium parvum, Entamoeba histolytica, Giardia lamblia, risk factors, Benue State, Nigeria.
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Full Length Research Paper
Abstract: As treatment of HIV infection with antiretroviral medications becomes a reality in sub-Saharan Africa, adherence to treatment regimen becomes a challenge. A meta-analysis was conducted to summarize the reported adherence rate in sub-Saharan Africa. Forest plot was used to visualize the extent of heterogeneity among studies. Following the random effect model, the combined adherence percent was 84.31% (95% CI = 79.48% - 88.60%). The Monte Carlo sensitivity analysis provided an alternative statistical method to evaluate pooled proportion and the analysis was similar to the random effect analysis. Identified barriers to adherence include: depression, centralized ART clinic, interruption in drug supply/procurement, stigma, absence of social support, cost of ART, complacency, forgetfulness and medication related problems. Cost of ART (OR = 2.19; 95% CI= 1.65 – 2.90), Complacency (OR = 5.25; 95% CI = 2.89 – 10.80), and medication related problems (OR = 1.68; 95%CI = 1.28 – 2.22) were the strongest barriers to adherence. This study showed a good level of adherence in sub-Saharan Africa. However, barriers to adherence identified in this study could be employed to improve adherence to a near perfect level.[...] Read More.
Keywords: Adherence, antiretroviral, Sub-Saharan Africa, HIV/AIDS, self-reported, meta-analysis.
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Full Length Research Paper
Abstract: Sickle cell disease is a genetic, hereditary and chronic disease that affects the health of its carriers and might impair their health-related quality of life. The aim of the current study was to determine the sickle cell trait frequency in Sudanese patient living in Heglig area in Western of Southern Kordofan state from November 2008 to February 2009. An analytical, descriptive and cross-sectional study conducted for one hundred participants who had confirmed patient diagnosed as (Hb S disease) homozygosis patient,2-5 mL of venous blood was collected for the measurements of complete blood count, sickling test and Hb electrophoresis. Demographic data and family history were collected in a pre designed questionnaire with written consent all participants. In this study the frequency of sickle cell trait and  sickle cell disease were (52%) and (14%) respectively and 34% were normal. The sickling test showed that 71 % of the study population were negative sickling test, the remaining  29 % were positive.  The total erythrocytes was significantly decreased in sickle cell disease (p< 0.000) compared with normal and sickle cell trait, also the hemoglobin concentration and packed cell volume were significantly lower than that of normal individuals and sickle cell trait patients. The frequencies of sickle cell trait was higher among the participants and patients of sickle disease showed lower values of red blood cells parameters , but higher values of white blood cells and platelets compared to haemoglobin phenotype AA control participants.[...] Read More.
Keywords: Sickle cell disease, Frequencies, Haematological values, Heglig , Sudan.  
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文章
 *A. U. Deore and S. B. Zade
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Beena E Thomas, Chandra Suresh, Sujatha V, Vijayalakshmi R, Basilea Watson and Soumya Swaminathan
Abstract: In the era of accessible antiretroviral treatment where HIV becomes a chronic disease, disclosure of parental HIV status to children is fraught with challenges. This study seeks to understand if parents disclose their HIV status to their children, and gain insight into some factors that influence disclosure. This is a cross sectional descriptive study on 115 of 136 HIV positive patients attending the outpatient clinic of the National Institute for Research in Tuberculosis (NIRT) situated in Chennai, South India. Disclosure was reported by twenty eight respondents (24%) of the respondents with 11(39%) who reported that it was done by them, the rest being unplanned or done by health providers. The most significant variables which influenced disclosure were age of the parents, (Adjusted OR = 14.7 C.I (3.2, 68), p-value: 0.001), divorced /widowed (Adjusted OR = 4.8, C.I (1.1, 22.1), p-value: 0.041) and having children ≥15 years (Adjusted OR = 3.1, C.I :( 1.1, 15.6), p-value: 0.043). It was also found that disclosure was more likely when both parents were positive. (c2 =7.481,p[...] Read More.
Keywords: Disclosure, Parents, HIV Status, children, Challenges. 
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