Antinociceptive activity of some 1,4-substituted piperidine derivatives using tail flick method in mice

Amirhossein Sakhteman¹, Mohammad Sharifzadeh², Alireza Moradi¹, Hamid Nadri¹, Kaveh Tabrizian^2,3, Massoud Amanlou⁴, Ali Asadipour⁵, Kouros Divsalar⁵, Abbas Shafiee⁴ and Alireza Foroumadi^4,5*

¹Department of Medicinal Chemistry, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

²Department of Pharmacology and Toxicology, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran.

³Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran.

⁴Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.

⁵Department of Medicinal Chemistry, Faculty of Pharmacy and Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.